Publications

Recent Publications (2009 onwards)

[1] Steephen, J. E., & Manchanda, R. (2009). Differences in biophysical properties of nucleus accumbens medium spiny neurons emerging from inactivation of inward rectifying potassium currents. Journal of computational neuroscience, 27(3), 453-470. Link

[2] Steephen, J. E. (2011). Excitability range of medium spiny neurons widens through the combined effects of inward rectifying potassium current inactivation and dopaminergic modulation. Neurocomputing, 74(18), 3884-3897. Link

[3] John, J., & Manchanda, R. (2011). Modulation of synaptic potentials and cell excitability by dendritic KIR and KAs channels in nucleus accumbens medium spiny neurons: a computational study. Journal of biosciences, 36(2), 309-328. Link

[4] John, J., Steephen, J. E., & Manchanda, R. (2013). Inactivation of KIR current modulates subthreshold synaptic inputs in striatal medium spiny neurons: A computational study. In World Congress on Medical Physics and Biomedical Engineering May 26-31, 2012, Beijing, China (pp. 2232-2235). Springer Berlin Heidelberg. Link

[5] Padmakumar, M., Bhuvaneshwari, K., & Manchanda, R. (2012, July). Classification and analysis of electrical signals in urinary bladder smooth muscle using a modified vector quantization technique. In 2012 International Conference on Signal Processing and Communications (SPCOM) (pp. 1-5). IEEE. Link

[6] Rane, M., Shah, A., Sheth, S., & Manchanda, R. (2012, February). Computational investigation of effects of UP state on EPSP in striatal Medium Spiny Neurons. In Biomedical Engineering (ICoBE), 2012 International Conference on (pp. 562-566). IEEE. http://ieeexplore.ieee.org/abstract/document/6178980/

[7] Gupta, S., & Manchanda, R. (2014, September). TANH Spline Interpolation for Analytical Modelling of BK Ion Channels in Smooth Muscle. In 2014 8th Asia Modelling Symposium (pp. 71-76). IEEE. Link

[8] Gupta, S., & Manchanda, R. (2014). A TANH Spline Interpolation for Modelling Ion Channels: Application to BK Channels in Smooth Muscle. International Journal of Simulation, Systems, Science & Technology. 15(6), 97-109. Link

[9] Appukuttan, S., Brain, K. L., & Manchanda, R. (2015). A computational model of urinary bladder smooth muscle syncytium. Journal of computational neuroscience,38(1), 167-187. Link

[10] Appukuttan, S., Brain, K., & Manchanda, R. (2015). Syncytial basis for diversity in spike shapes and their propagation in detrusor smooth muscle. Procedia Computer Science, 51, 785-794. Link

[11] Appukuttan, S., Sathe, R., & Manchanda, R. (2015). Modular approach to modeling homotypic and heterotypic gap junctions. In Computational Advances in Bio and Medical Sciences (ICCABS), 2015 IEEE 5th International Conference on (pp. 1-6).IEEE. Link

[12] Mahapatra, C., Brain, K. L., & Manchanda, R. (2015, April). Computational studies on urinary bladder smooth muscle: Modeling ion channels and their role in generating electrical activity. In Neural Engineering (NER), 2015 7th International IEEE/EMBS Conference on (pp. 832-835). IEEE. Link

[13] Dave, V., Mahapatra, C., & Manchanda, R. (2015 August). A mathematical model of the calcium transient in urinary bladder smooth muscle cells. In Engineering in Medicine and Biology Society (EMBC), 2015 37th Annual International Conference of the IEEE (pp. 5359-5362). IEEE. Link

[14] Mandge, D., & Manchanda, R. (2015, August). Computational studies on bladder small dorsal root ganglion neurons: Modelling BK channels. In Engineering in Medicine and Biology Society (EMBC), 2015 37th Annual International Conference of the IEEE (pp. 5376-5379). IEEE. Link

[15] Padmakumar, M., Brain, K. L. and Manchanda, R. “Classification of Cells in Detrusor Smooth Muscle Syncytium Based on Analysis of Spontaneous Electrical Activities,” IEEE RAICS 2015, Trivandrum, 11-13 Dec 2015. Link

[16] Rane, M., & Manchanda, R. (2015). Computational Investigation of Effects of Spines and AMPA Receptor Desensitization in Temporal Integration in Striatal Medium Spiny Neurons. Link

[17] Sengupta, N., Brain, K. L., & Manchanda, R. (2015, August). Spatiotemporal dynamics of synaptic drive in urinary bladder syncytium: A computational investigation. In Engineering in Medicine and Biology Society (EMBC), 2015 37th Annual International Conference of the IEEE (pp. 8074-8077). IEEE. Link

[18] Appukuttan, S., & Manchanda, R. (2016). Independence of AP propagation velocity to transjunctional voltage dependence of gap junctional coupling. The Siberian Scientific Medical Journal, 36(1), 80-85. Link

[19] Appukuttan, S., Sathe, R., & Manchanda, R. (2016). Influence of Gap Junction Subtypes on Passive and Active Electrical Properties of Syncytial Tissues. IEEE International Conf. on Systems in Medicine and Biology 2016 (ICSMB ’16), Kharagpur, 4 – 7 Jan 2016. Link

[20] Gupta, S., & Manchanda, R. (2016 February). Computational Model of SK Channel with reference to Calcium Dynamics in Bladder Smooth Muscles. In The 12th IASTED International Conference on Biomedical Engineering (BioMed) 2016 (pp. 53 – 59). Link

[21] Padmakumar, M., Brain, K. L., and Manchanda, R. “Feature Detection and Classification of Action Potentials from Detrusor Smooth Muscle Cells,” IEEE International Conf. on Systems in Medicine and Biology 2016 (ICSMB ’16), Kharagpur, 4 – 7 Jan 2016. Link

[22] Padmakumar, M., Jacob, B. ,Venkatakrishnan, R., Brain, K. L. and Manchanda, R. “Unsupervised Classification of Spontaneous Action Potentials in Urinary Bladder,” International Journal of Computer Theory and Engineering vol. 9, no. 2, pp. 115-122, 2016.

[23] Mandge, D., Bhatnagar, A. and Manchanda, R. “Computational Model for Intercellular Communication between DRG Neurons via Satellite Glial Cells using ATP.” 2017 8th International IEEE/EMBS Conference on Neural Engineering (NER), Shanghai, 2017. Link

[24] Aruljothi, S., Mandge, D., and Manchanda, R. “A Biophysical Model of Heat Sensitivity in Nociceptive C-Fiber Neurons.” 2017 8th International IEEE/EMBS Conference on Neural Engineering (NER), Shanghai, 2017. Link

[25] Gupta, Suranjana, Avni Majawadia, and Rohit Manchanda. “A computational model of intracellular calcium oscillations in urinary bladder smooth muscle cells.” Engineering in Medicine and Biology Society (EMBC), 2017 39th Annual International Conference of the IEEE. IEEE, 2017. Link

[26] Dave, V., & Manchanda, R. (2017). A computational model of the Ca2+ transients and influence of buffering in guinea pig urinary bladder smooth muscle cells. Journal of bioinformatics and computational biology, 15(03), 1750011. Link

[27] Appukuttan, S., Brain, K. L., & Manchanda, R. (2017). Modeling extracellular fields for a three-dimensional network of cells using neuron. Journal of Neuroscience Methods, 290, 27-38. Link

[28] Appukuttan, S., Brain, K., & Manchanda, R. (2017). Investigation of action potential propagation in a syncytium. Biomed. Res. J, 4(1), 102-115. Link

[29] Appukuttan, S., Padmakumar, M., Brain, K. L., & Manchanda, R. (2017). A Method for the Analysis of AP Foot Convexity: Insights into Smooth Muscle Biophysics. Frontiers in bioengineering and biotechnology, 5. Link

[30] Padmakumar, M., Brain, K. L., Young, J. S., & Manchanda, R. (2018). A four-component model of the action potential in mouse detrusor smooth muscle cell. PloS one, 13(1), e0190016. Link

[31] Mahapatra, C., Dave, Vijay., & Manchanda, R.“A mathematical modeling of voltage gated calcium ion channel based calcium transient response in urinary bladder smooth muscle cell”, International Journal of Pure and Applied Mathematics. Link

[32] Mahapatra, C., & Manchanda, R. (2017). Simulation of In Vitro-Like Electrical Activities in Urinary Bladder Smooth Muscle Cells. In Journal of Biomimetics, Biomaterials and Biomedical Engineering (Vol. 33, pp. 45-51). Trans Tech Publications. Link

[33] Manchanda, R., Brain, K. L., & Mahapatra, C. (2016, August). Computational study of ATP gated Potassium ion channel in urinary bladder over activity. In Inventive Computation Technologies (ICICT), International Conference on(Vol. 2, pp. 1-4). IEEE. Link

[34] Mahapatra, C., & Manchanda, R. (2016, August). Computational simulation of spike patterns in STN neuron using Izhikevich model. In Inventive Computation Technologies (ICICT), International Conference on (Vol. 2, pp. 1-4). IEEE. Link

[35] Mahapatra, C., Brain, K. L., & Manchanda, R. (2018). A biophysically constrained computational model of the action potential of mouse urinary bladder smooth muscle. PloS one13(7), e0200712. Link

[36] Mandge, D., & Manchanda, R. (2018). A biophysically detailed computational model of bladder small DRG neuron soma. PLoS computational biology14(7), e1006293. Link

Abstracts

[1] Mahapatra, C., & Manchanda, R. (2017). MP42-01 QUANTITATIVE STUDY OF INWARD RECTIFYING ION CHANNEL IN DETRUSOR INSTABILITY. The Journal of Urology, 197(4), e544. Link

[2] Mahapatra, C., Brain, K. L., & Manchanda, R. (2016, August). ELECTROPHYSIOLOGICAL MODELING OF ELECTRICAL ACTIVITIES IN DETRUSOR SMOOTH MUSCLE CELLS: ROLE OF PURINERGIC SYNAPTIC INPUT IN SHAPING ACTION POTENTIAL. In NEUROUROLOGY AND URODYNAMICS (Vol. 35, pp. S332-S333). 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: WILEY-BLACKWELL. Link

[3] Mahapatra, C., & Manchanda, R. (2015). Computational Studies on Bladder Smooth Muscle: Modeling Ion Channels and their Role in Generating Electrical Activity. Biophysical Journal, 108(2), 588a. Link